VP Engineering - AI

Acceler8 Talent
Cambridge, MA

VP Engineering

AI-First Platform | Cambridge, MA (Hybrid)


I’m working with a highly backed venture builder at the forefront of AI and scientific innovation. They create and scale AI-native companies across areas like life sciences, health, and sustainability - and are hiring a VP of Engineering to define and lead their core platform.


🚀 What makes this different

  • You’ll lead a team made up entirely of Principal Engineers - no hierarchy, no hand-holding, just high-calibre technical operators
  • Remain hands-on (~25%), contributing directly to architecture and complex system design
  • Build systems used by scientists and domain experts, not just typical SaaS users
  • Operate in a truly AI-native engineering environment, where AI tooling is central to how software gets built


🧠 The role

  • Own technical strategy and architecture for a portfolio-wide AI platform
  • Hire, lead, and develop a small, elite engineering team
  • Make critical decisions on system design, scalability, and build vs. buy
  • Work closely with product and research stakeholders to translate complex ideas into production systems
  • Dynamically allocate engineering resources across multiple high-impact initiatives


🔧 What’s technically interesting?

  • Building AI-first systems from scratch, not layering ML onto legacy infrastructure
  • Designing platforms that enable rapid company creation and experimentation
  • Solving complex, real-world problems in ambiguous, fast-moving environments
  • Empowering engineers to act as true end-to-end technical owners
  • Driving adoption of AI-augmented development workflows at scale


👤 What they’re looking for

  • Experience leading senior/principal engineers in high-performance teams
  • Strong system design and architectural expertise
  • Background in startup or high-autonomy environments
  • Ability to balance hands-on technical work with strategic leadership
  • Nice to have: experience building products for scientific or research users


🌍 Why join?

  • Shape the engineering foundation behind a portfolio of AI-driven companies
  • Work with exceptional engineers, researchers, and founders
  • High autonomy, high impact, minimal bureaucracy
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