Sr. Biopharmaceutical Processing Technician

Senior Biopharmaceutical Processing Technician

Upstream Cell Culture & Large‑Scale Manufacturing

Are you passionate about biologics and large‑scale biomanufacturing? As a Senior Biopharmaceutical Processing Technician, you’ll play a hands-on role in producing life‑changing biologic medicines used in both commercial and clinical settings. Working in a cGMP‑regulated cleanroom, you’ll focus primarily on upstream cell culture operations, operating large‑scale bioreactors and supporting critical production processes from start to finish.

This is an excellent opportunity to deepen your experience with advanced bioprocessing technologies, contribute directly to pharmaceutical products, and work alongside a collaborative, quality‑driven manufacturing team.

What You’ll Do

You will be a key contributor to safe, efficient, and compliant manufacturing operations, with responsibilities that include:

• Execute manufacturing batch records, work instructions, and SOPs with a proactive “right‑the‑first‑time” mindset
• Perform aseptic cell culture operations, including propagation of mammalian cell lines
• Operate and monitor large‑scale production bioreactors (50L–2000L) and associated upstream equipment
• Conduct large‑scale filtration and centrifugation as part of upstream bioprocessing workflows
• Interpret production schedules, prioritize tasks, and meet manufacturing timelines

• Accurately document all activities in compliance with cGMP requirements
• Assist with batch record reconciliation and ensure complete, accurate documentation
• Complete document reviews and revisions, including daily record review, task tracking, and database updates
• Support quality investigations by providing clear information and improvement recommendations

• Support department functions such as maintaining production suites, equipment, logbooks, and supplies
• Participate in and, when needed, lead shift exchanges, one‑on‑one discussions, and team meetings
• Engage in continuous improvement and lean initiatives to enhance quality and efficiency
• Critically evaluate processes, anticipating potential issues before they occur

• Apply consistent aseptic technique to protect product quality and prevent contamination
• Promote and follow all safety procedures and cleanroom guidelines
• Maintain a strong commitment to quality, accuracy, and compliance

What You Bring (Essential Qualifications)

• Bachelor of Science diploma or equivalent
• Minimum 2 years of experience in manufacturing, operations, production, laboratory, or related environments
• Ability to work in a cGMP‑regulated environment and follow detailed procedures
• Strong basic math skills to support calculations and measurements
• Proficiency with MS Office for documentation and communication
• Demonstrated critical thinking and problem‑solving skills
• Ability to read, write, and communicate effectively in English
• Ability to understand and accurately follow written and verbal instructions
• Ability to:
  • Wear full cleanroom gowning (bodysuit, gloves, hair/beard nets, face covers, safety glasses, Tyvek garments)
  • Lift at least 25 pounds independently
  • Stand for approximately 80% of the shift
  • Work rotating 12‑hour shifts, including days or nights and alternating weekends

Work Environment & Schedule

This role is based in a cleanroom and aseptic suite, requiring strict adherence to gowning and contamination‑control procedures. Full gowning is required, and personal items such as makeup, jewelry, nail polish, perfume/cologne, and scented products are not permitted in production areas.

• Schedule: Rotating 12‑hour shifts
  • Day: 6:45 a.m. – 6:45 p.m.
  • Night: 6:45 p.m. – 6:45 a.m.
• Typical rotation: 7 working days over a 2‑week period
• Physically active role involving prolonged standing and lifting

This is a Contract to Hire position based out of Saint Louis, MO.

The pay range for this position is $28.00 - $28.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:
• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

This is a fully onsite position in Saint Louis,MO.

This position is anticipated to close on May 1, 2026.

Diversity, Equity & Inclusion

At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I is embedded into our culture through:

• Hiring diverse talent
• Maintaining an inclusive environment through persistent self-reflection
• Building a culture of care, engagement, and recognition with clear outcomes
• Ensuring growth opportunities for our people

Actalent is an equal opportunity employer.

About Actalent

Actalent is a global leader in engineering and sciences services. For more than 40 years, we’ve helped visionary companies advance their goals. Headquartered in the United States, our teams span 150 offices across North America, EMEA, and APAC—with four delivery centers in India led by 1,000+ extraordinary employees who connect their passion with purpose every day.

Our Bangalore, Hyderabad, Pune, and Chennai delivery centers are hubs of engineering expertise, with core capabilities in mechanical and electrical engineering, systems and software, and manufacturing engineering. Our teams deliver work across multiple industries including transportation, consumer and industrial products, and life sciences. We serve more than 4,500 clients, including many Fortune 500 brands. Learn more about how we can work together at actalentservices.com.