Senior Program Manager – Large-Scale Capital Projects

Senior Program Manager – Large-Scale Capital Projects

Overview

We are seeking a Senior Program Manager to lead complex, large-scale capital projects within a pharmaceutical manufacturing environment. This role oversees $100M+ CAPEX programs, driving execution across multiple workstreams while ensuring schedules, deliverables, and quality standards are met. This is a high-visibility opportunity to contribute to a major site expansion initiative.

Key Responsibilities

• Lead end-to-end execution of large-scale CAPEX programs ($100M+) within a GMP-regulated environment
• Own program timelines, deliverables, and cross-functional coordination across multiple workstreams
• Partner with Engineering, Validation, Quality, Manufacturing, and external vendors
• Provide both strategic direction and hands-on leadership throughout the full project lifecycle
• Drive accountability across stakeholders with minimal oversight
• Proactively identify risks, mitigate issues, and maintain alignment with business objectives
• Communicate program status clearly to senior leadership and project teams
• Ensure compliance with GMP, regulatory, and quality standards

Required Qualifications

• 15–25+ years of experience managing large capital projects or programs
• Proven experience leading $100M+ CAPEX initiatives
• Pharmaceutical manufacturing experience required
• Strong background working in GMP-regulated environments
• Demonstrated ability to lead complex, high-visibility initiatives with minimal oversight
• Excellent communication and stakeholder management skills

Preferred Experience

• API (Active Pharmaceutical Ingredient) manufacturing experience (highly preferred)
• Fill-finish, parenteral manufacturing, or GMP device assembly experience
• Experience supporting site expansions, greenfield, or brownfield builds

Soft Skills & Key Attributes

• Highly motivated, self-starter mindset
• Ability to hit the ground running in fast-paced environments
• Comfortable operating in high-pressure, evolving programs
• Strong problem-solving skills and ability to navigate ambiguity
• Team-oriented leader motivated by high-impact work

Work Environment

• On-site role in Richmond, VA supporting a large-scale pharmaceutical site expansion
• Full-time on-site presence required, particularly during initial project phases