JOB TITLE: Assistant / Associate Scientist
Location: East Syracuse, NY
Duration: 12 months initial (potential extension/potential right to hire)
Position Summary:
The Primary role of the Downstream Associate Scientist is to execute lab scale experiments in the downstream development process such as buffer preparation, chromatography, filtration processes, TFF. Experiment will be executed and documented in laboratory notebooks and ELN to follow detailed. Fast paced environment flexibility is essential.
Responsibilities:
• Execute downstream purification experiments including chromatography (affinity, ion exchange, HIC) and filtration techniques (TFF, depth filtration).
• Assist in process development, optimization, and scale-up of purification processes for proteins, antibodies, or other biologics.
• Prepare large volumes of buffer and maintain appropriately required documentation.
• Operate and maintain AKTA systems and other purification equipment.
• Analyze experimental data, interpret results, and present findings to internal teams.
• Support technology transfer activities from development to manufacturing.
• Draft and review technical documents including protocols, reports, SOPs, and batch records.
• Ensure compliance with company and regulatory quality standards as applicable.
• Troubleshoot process issues and propose scientifically sound solutions.
• Collaborate with upstream, analytical, and manufacturing teams to ensure seamless project progression.
• Maintain accurate and timely documentation in physical and/or electronic lab notebooks.
• Perform routine laboratory activities including sample management, instrument maintenance and calibration, inventory and ordering of supplies, general housekeeping, and other related activities.
Quals--
Education:
Bachelor’s or Master’s degree in Biochemistry, Biotechnology, Chemical Engineering, or a related field.
Technical Skills
• Hands-on experience with chromatography systems (e.g., AKTA).
• Knowledge of protein purification techniques and principles.
• Familiarity with filtration methods including ultrafiltration/diafiltration (UF/DF).
• Familiarity with buffer preparation
• Basic understanding of analytical methods (e.g., HPLC, SDS-PAGE, UV-Vis).
• Experience with data analysis tools (e.g., Excel, JMP, or similar).
Experience:
• 0–3 years (Associate level) of relevant industry or academic experience in downstream processing.
• Experience in a CDMO or biopharmaceutical environment is a plus.
Physical Demands:
• Laboratory-based position which requires appropriate levels of personal protective equipment (PPE). This role may require contact with biohazardous materials such as live cell cultures and other hazardous chemicals including methotrexate, acids, and caustics. Powdered materials and high temperature liquids and solids may also be handled
• Frequent repeated motions such as pipetting, lifting, bending, twisting, squatting, crouching, kneeling, climbing on step stools, and reaching may be required. This role may also require unassisted lifting (not to exceed 50 lbs). Repetitive use of arms/hands/wrists and grasping may also be required
• The position is based indoors and the individual will primarily be working with others, but also independently and alone at times in the laboratory
• The office-based work will require sitting
• Dynamic, fast-paced, interactive, and entrepreneurial environment
Work Environment:
• Laboratory-based position which requires appropriate levels of personal protective equipment (PPE). This role may require contact with biohazardous materials such as live cell cultures and other hazardous chemicals including methotrexate, acids, and caustics. Powdered materials and high temperature liquids and solids may also be handled• Frequent repeated motions such as pipetting, lifting, bending, twisting, squatting, crouching, kneeling, climbing on step stools, and reaching may be required. This role may also require unassisted lifting (not to exceed 50 lbs). Repetitive use of arms/hands/wrists and grasping may also be required
• The position is based indoors, and the individual will primarily be working with others, but also independently and alone at times in the laboratory
• The office-based work will require sitting
• Dynamic, fast-paced, interactive, and entrepreneurial environment
If hired, you will enjoy the following Eclaro Benefits:
If you feel you are qualified with the required skills and if you are interested, please free to send your word version most updated resume TAILORED to the job description above to June@eclaro.com or call (212)804-7476.
Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.