Biologist

Binding Minds Inc. (Certified Disability Owned Business Enterprise)
Boston, MA

Job Requirements

  • B.S. and/or M.S. in Biological Sciences, Biochemistry, or a related field with 3–5 years of laboratory research experience.
  • Strong expertise in molecular biology techniques including nucleic acid extraction and purification, quantification, NGS library preparation/QC, and qPCR.
  • Hands-on experience with next-generation sequencing (NGS) technologies and applications, including sequencing, quantification, and data QC, preferably using Illumina platforms.
  • Direct experience with bulk RNA-seq and amplicon-seq workflows.
  • Required experience in single-cell and single-nucleus RNA-seq library preparation.
  • Familiarity with multiple scRNA-seq/snRNA-seq platforms such as 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences.

Preferred Qualifications

  • Experience with CRISPR-based gene editing and high-throughput screening is a plus.
  • Exposure to laboratory automation systems including Mantis, Integra systems, Liquid Handlers, SPTLabtech Firefly, Tecan, or similar platforms is preferred.
  • Strong organizational, communication, and time management skills.
  • Experience maintaining documentation in electronic laboratory notebook systems.

Responsibilities

  • Support research and early clinical development programs focused on biologics, small molecules, oligonucleotides, and cell therapies targeting diabetes, obesity, cardiovascular disease, and metabolic disorders.
  • Perform RNA-seq, scRNA-seq, snRNA-seq, and other sequencing library preparation workflows to support multiple therapeutic area research groups.
  • Conduct molecular and cell biology experiments to identify and validate drug targets.
  • Assist with assay design, optimization, validation, troubleshooting, and data analysis in support of drug discovery initiatives.
  • Analyze complex experimental data and present findings through written summaries and oral presentations.
  • Collaborate cross-functionally with research teams to support scientific and operational goals.
  • Maintain accurate experimental records and documentation in compliance with laboratory standards.

The ideal candidate will bring strong technical expertise in next-generation sequencing workflows along with the ability to operate effectively in a fast-paced research environment.

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