Senior Scientist

Title : Scientist 3

Location: Spring House PA

Duration: 8+ months

Pay rate : $61/hr on w2

Job Overview

Join a dynamic team developing state-of-the-art automation systems for mass spectrometry applications in biotherapeutics cell line development.

This role focuses on advancing next-generation automation solutions to support the Cell Engineering and Analytical Sciences group. You will work at the intersection of robotics, sample preparation, method development, and data analysis in a fast-paced, innovative environment.

Key Responsibilities

• Operate and validate automated robotic workflows; monitor system performance, document deviations, and implement corrective actions.
• Develop and execute mass spectrometry assays to optimize protein expression, assess protein quality, and quantify biotherapeutics.
• Ensure high-quality MS results through strong expertise in sample preparation techniques.
• Deploy, optimize, maintain, and continuously improve high-throughput workflows using liquid-handling robots and integrated automation systems.
• Perform antibody analysis using peptide mapping, intact mass analysis, native mass spectrometry, and acoustic ejection mass spectrometry.
• Troubleshoot instrumentation issues by collaborating with internal experts and external vendors; conduct root cause analyses based on scientific and technical investigations.
• Analyze data and present findings, insights, and recommendations to project teams, stakeholders, and senior management.

Qualifications

• Bachelor’s degree in Biology, Chemistry, Computer Science, Engineering, or a related field (advanced degree preferred).
• Hands-on experience with laboratory protocols, including pipetting and protein sample handling.
• Experience operating liquid-handling systems (e.g., Hamilton, Tecan, Beckman) is highly desirable.
• Basic programming experience (Python, JavaScript, R, C++, or C#) is a plus.
• Practical experience with LC-MS and associated sample preparation techniques.