The Senior Scientist will be a key member of the team, focusing on downstream activities. During this exciting period of growth, you will play a critical part in supporting our Phase III program as it advances toward commercialization, ensuring robust and scalable manufacturing processes. This is a 12-month contract based in Redwood City, CA.
Responsibilities
- Perform pilot scale downstream purification process and manufacturing (post cell lysate to final formulation) by utilizing column chromatography, Ultrafiltration (UF) and Diafiltration (DF), and various filtration steps.
- Follow good documentation practices to maintain accurate records.
- Work closely with team members to perform buffer preparation.
- Set-up, operate and maintain required downstream laboratory equipment.
- Maintain reagent, sample, and consumables inventory.
- Assist with data entry and data analysis in Excel and/or other statistical programs.
- Ensure safe workplace in compliance with the company and EHS' rules and regulations.
- Work with Assay Development and Quality Control to coordinate testing.
- Work to optimize, and revise current process protocols, procedures, and batch records to make them more robust and streamlined.
Qualifications
- Bachelor’s or advanced degree in chemical/biochemical engineering or related fields.
- 6-8 years of downstream purification experience in pharmaceutical or gene therapy manufacturing, including GMP-regulated operations.
- Hands on experience with buffer preparations, TFF (Hollow Fiber/Cassettes), UF/DF and Column Chromatography Purification.
- Experience working with AKTA Avant is required.
- Able to work in a fast-paced environment as a team player with effective communication skills.
- Excellent computer skills; especially proficient in Excel and Word.
- Experience with statistical analysis software (e.g., JMP) and data visualization tools is a plus.
- Strong desire to learn new technologies, skill sets, and science behind AAV processing.
- Strong teamwork and communication skills.
- Familiarity with regulatory guidelines and requirements for biologics manufacturing is a plus.
- Some overtime required, as needed.
Salary
Why Choose R&D Partners?
As an employee, you have access to a comprehensive benefits package including:
- Medical insurance – PPO, HMO & HSA
- Dental & Vision insurance
- 401k plan
- Employee Assistance Program
- Long-term disability
- Weekly payroll
- Expense reimbursement
- Online timecard approval
R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.
R&D Partners is an equal-opportunity employer.
