Senior Scientist - Oligo Bioinformatics

Work Location: Billerica, Massachusetts
Shift: No
Department: HC-RD-XO4 Oligonucleotide Chemical Conjugation
Recruiter:Beverly Dellisola

This information is for internals only. Please do not share outside of the organization.

Your Role:

EMD Serono in Billerica, MA is seeking a Senior Scientist – Oligo Bioinformatics to add to their Oligonucleotide Therapeutics Group (DDTech).

Responsibilities:

• Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes
• Design and build pipelines that process and analyze related data, store summary results and integrate with the corporate ELN
• Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes
• Develop, deploy, manage, and run applications using Docker containers
• Discovery and development of oligonucleotide therapeutics

Who You Are:

Minimum Qualifications:

• PhD in Chemistry, Chemical Engineering, Computer Science or other Science field with 3+ years of direct experience in siRNA/ASO/SSO

Preferred Qualifications:

• Experience with common human genetics resources and techniques
• Deployment of interactive applications from scripting languages like R and Python (Shiny and streamlit)
• Experience with relational databases; hands on experience with MySQL
• Experience in common NGS analyses task such mapping reads, quantification of gene expression, and/or variant calling
• Experience with common bioinformatics tools like Samtools, GATK, Bowtie, HISAT2, BLAST, htseq-count, DESeq, Salmon, STAR, or Subread
• Knowledge of Illumina sequencing data analysis is necessary and experience with PacBio and/or Nanopore sequencing
• Familiarity with UNIX computing environment and proficiency in either Python or R scripting
• Experience with docker and Nextflow pipeline
• Ability to communicate finding of NGS data to a general scientific audience in both oral and written forms

Pay Range for this position: $111,100 - $166,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here

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