Senior Research Scientist, Predictive Synthesis (Discovery Chemistry)

Insight Global
Collegeville, PA

Senior Research Scientist, Predictive Synthesis (Discovery Chemistry)



The Senior Research Scientist will support a project within the Predictive Synthesis team in R&D Discovery Chemistry. This individual will be responsible for executing high‑throughput, nano‑scale synthetic chemistry experiments using automated, plate‑based workflows to rapidly generate high‑quality experimental data. The role is highly hands‑on and execution‑focused, requiring strong attention to detail, comfort with automation, and the ability to operate independently in a fast‑paced discovery environment.


Key Responsibilities

  • Execute high‑throughput synthetic chemistry experiments using automated, plate‑based workflows (e.g., 1536‑well formats).
  • Run nano‑scale chemical reactions using liquid handlers, gloveboxes, and laboratory automation platforms.
  • Learn and execute predictive synthesis workflows to support discovery decision‑making.
  • Deliver consistent experimental output, with expectations to complete two 1536‑well plates per week (~3,000 data points).
  • Independently order reagents and building blocks required for experimental execution.
  • Accurately document experiments, results, and observations in the appropriate Electronic Laboratory Notebook (ELN) in accordance with internal standards.
  • Ensure data quality, reproducibility, and traceability across all experiments.
  • Collaborate with discovery chemistry and predictive synthesis teams to support project objectives.
  • Follow laboratory safety requirements, SOPs, and data governance expectations.



Required Qualifications

  • Bachelor’s, Master’s, or PhD in Chemistry or a related scientific discipline.
  • A PhD is common, but not required with strong relevant experience.
  • Hands‑on experience in synthetic organic chemistry within an academic or industry setting.
  • Demonstrated exposure to high‑throughput or parallel chemistry, reaction miniaturization, or plate‑based experimentation.
  • Experience working with automation, liquid handling systems, or high‑throughput laboratory workflows.



Compensation:

$40-60/hr


Exact compensation may vary based on several factors, including skills, experience, and education.


Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.

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