Scientist, Bioanalytical Contractor

Our Boston area client is seeking a contractor Bioanalytical Scientist to support assay development, validation, and sample analysis for RNA‑ and oligonucleotide‑based therapeutics. You’ll collaborate across research and in‑vivo teams, manage CRO assay transfer/validation, and ensure high‑quality data delivery. This role reports to the Senior Director of Bioanalytical.

Key Responsibilities

• Develop and validate assays to quantify oligonucleotides and protein biomarkers for ADME and pharmacology studies.
• Perform PK/PD and non‑clinical sample analysis; interpret and report data.
• Prepare method protocols and technical documentation.
• Present results in team and lab meetings.
• Support in‑vivo pharmacology and research teams.
• Manage CRO assay transfer, qualification/validation, and project tracking.
• Maintain accurate ELN records and support daily lab operations.

Required Skills & Experience

• Bachelor’s (10+ yrs), Master’s (8+ yrs), or Ph.D. (2+ yrs) in a relevant field.
• Strong hands‑on experience with ligand‑binding assays (ELISA, MSD‑ECL).
• Experience with nucleic acid therapeutic bioanalysis (HELISA, H‑ECL) preferred.
• Solid understanding of assay development, validation, and ADME principles.
• LC‑MS experience is a plus.
• Familiarity with GLP, ICH, FDA guidance; regulated lab experience is a plus.
• Excellent problem‑solving, communication, and documentation skills.
• Proficiency with Word, Excel, PowerPoint, and GraphPad.