Postdoctoral Scientist - AAV Gene Therapy/Extracellular Vesicles/Translational Research

Summary

Dr. Nizar Saad’s lab is seeking a postdoctoral scientist to join a translational research program advancing RNA-based and genome-editing therapies for rare genetic diseases. The lab develops RNA-, and CRISPR-based approaches for laminopathies and muscular dystrophies, using viral and non-viral delivery platforms (i.e., AAV and extracellular vesicles (EVs)). The lab also leads EV-based biomarker discovery efforts in muscular dystrophies.

This position will require experience in EV and/or AAV isolation, purification, and characterization, -omics workflows, mouse work, including dosing and tissue collection. Experience in EV and/or AAV engineering is desired. Experience in cardiovascular or skeletal muscle biology is preferred. Additional details at these links: NIH-funded grant and Saad Lab page.

Essential Functions

• Conducts research under the guidance of a faculty mentor.
• Assists in the training and supervision of technical support staff in performing research essential to carrying out the research program.
• Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
• Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
• Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
• Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.

Education

• PhD in relevant scientific field.

Skills

• Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
• Excellent computer skills.
• Skills in qualitative and quantitative research methods.
• Ability to proactively manage and drive projects.

Experience:

• Research experience from PhD program required