Contract Scientist – Cell Line Engineering
Location: Worcester, MA (Onsite)
Duration: 12‑month contract
Pay Rate: $45–46/hr (with benefits)
Position Overview
We are seeking a Contract Scientist to join the Cell Line Engineering group within Biotherapeutics Discovery. This team plays a critical role in generating cellular reagents that support a wide range of applications across the therapeutic development process.
Working under the supervision of a senior scientist, this individual will support mammalian cell culture, cell line engineering, cell-based assays, and flow cytometry, while also contributing to lab operations and digital cell line inventory initiatives. This role offers hands-on exposure to cutting-edge cell and molecular biology technologies in an industry research setting.
Key Responsibilities
- Perform mammalian cell culture (immortalized, cancer, and primary cell lines)
- Generate, maintain, and bank engineered KO, KI, and OE cell lines
- Support antibody discovery and assay development programs
- Perform flow cytometry (FACS) analysis, cell sorting, and cloning
- Execute and support cell-based assays
- Contribute to technology development for cell line engineering
- Expand and bank core cell lines to ensure sufficient inventory
- Consolidate historical and current cell line assets into a digital inventory system
- Coordinate cell line inventory across multiple sites to support future Cell Bank initiatives
- Assist with general lab and inventory management
Required Qualifications
- 3–5 years of hands-on experience, preferably in an industry setting
- Strong experience with:
- Mammalian cell culture
- Cell line engineering
- CRISPR/Cas9 gene editing
- Flow cytometry / FACS
- Cell-based assays
- Solid foundation in cell and molecular biology
- Ability to work collaboratively in a fast‑paced research environment
Nice to Have
- Vector design or genome engineering experience
- Cell cloning and receptor density quantification
- Exposure to discovery or therapeutic development research
