Sr Associate Scientist – Purification Process Development
Foster City (Onsite – 5 days/week)
1-Year Contract
Position Summary
We are seeking a highly motivated Sr Associate Scientist to support downstream purification process development for biologics during pivotal and commercial development stages.
This is a hands-on laboratory-based role focused on bench-scale purification development, process characterization, and experimental execution in a fast-paced GMP-aligned environment.
The ideal candidate will have strong technical expertise in chromatography, filtration, and UF/DF operations, along with the ability to independently execute, troubleshoot, and optimize purification processes.
Core Responsibilities (Simplified)
Purification Development
- Execute bench-scale downstream purification (chromatography, filtration, UF/DF)
- Support process characterization, robustness, resin/membrane lifetime studies
- Generate and interpret experimental data under data integrity standards
Lab & Technical Execution
- Troubleshoot AKTA-based purification systems and workflows
- Improve reproducibility and process robustness
- Maintain lab readiness, instruments, and documentation (ELN, protocols, reports)
Cross-functional Support
- Collaborate with upstream/downstream teams
- Support implementation of new purification technologies
Must-Have Skills (Screening Critical)
Look for candidates with:
- MS + 4 yrs OR BS + 6 yrs relevant biotech/pharma experience
- Strong hands-on downstream purification experience
- Chromatography (Protein A, IEX, HIC, SEC ideally)
- Filtration + UF/DF (tangential flow filtration/TFF)
- Experience executing lab-scale purification experiments independently
- Strong data analysis + ELN documentation discipline
Nice-to-Have
- AKTA system experience
- UNICORN software proficiency
- Experience in process characterization / late-stage development
- Resin/membrane lifetime or robustness studies
- Exposure to commercial/clinical biologics development
